Sedation in children: The typical dose is 12.5 to 25 mg by mouth, rectally, or injected into a muscle before sleep.If you are taking this to treat anxiety before surgery, the dose is usually 50 mg by mouth or rectally the night before your procedure. Sedation in adults: The typical dose is 25 to 50 mg by mouth, rectally, or injected into a muscle before sleep.It should be given as little as possible, but no more than every 4 hours. Nausea and vomiting in children (dose based on weight): The typical dose is 0.5 mg per pound of body weight by mouth or rectally.Nausea and vomiting in adults: The typical dose is 12.5 to 25 mg by mouth, rectally, or injected into a muscle every 4 to 6 hours as needed.Motion sickness in children: The typical dose is 12.5 to 25 mg by mouth or rectally up to twice a day.If you need to take it daily (for example, while on a cruise), you would typically take 25 mg by mouth or rectally two times a day (first thing in the morning and after your evening meal). You can repeat this every 8 to 12 hours as needed. Motion sickness in adults: The typical dose is 25 mg by mouth or rectally 30 to 60 minutes before traveling.This can be repeated every 2 hours if needed. Allergic reactions: The typical dose is 25 mg injected into a muscle as soon as possible after the reaction starts.
You can take 25 mg by mouth or rectally at bedtime OR 12.5 mg by mouth or rectally before meals and at bedtime OR 6.25 to 12.5 mg by mouth or rectally 3 times a day as needed. Allergies: Promethazine can be taken a few different ways to treat allergies.
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